Clinical Research
Clinical Research Papers
Suprasystolic dP/dt max
Obtained by Cuff Sphygmomanometer Traces Discriminates Subjects
with Impaired Contractile Cardiac Function
M Muscolo, G Germano, S Angotti, V
Pecchioli, A scuteri, U Germano, M Giordano - Universita "La
Sapienza" Policlinico Umberto I, Rome (Italy)
Technological
evolution allowed to record high fidelity traces that - when
analyzed by complex mathematical systems - may provide extremely
detailed and new information about all the factors involved in
the determinism of pulse wave. Suprasystolic waves, i.e. those
recorded immediately before systolic pressure, may be regarded as
similar to aortic pressure waves evaluated during cardiac
catheterization. Suprasystolic dP/dt max was calculated from the
profile of pulse wave recorded by the DynaPulse® (an automatic non-invasive oscillometric
method to simultaneously measure BP and analyze arterial
waveforms) in 10 normal healthy subjects and 5 subjects with
dilative cardiomyopathy whose ejection fraction - invasively
assessed -0 was < 40%. The mean suprasystolic dP/dt max was
405 ± 120 in normal subjects and 267 ± 135 mmHg/sec (p<0.05) in patients with
cardiomyopathy and reduced ejection fraction. In conclusion, \we
found a significant difference in the suprasystolic dP/dt max
values between healthy subjects and patients with impaired
cardiac function.
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