Clinical Research
Clinical Research Papers
This page summarizes the clinical works of Pulse Metric, Inc. and its joint research partners presented or published worldwide since 1994. Research topics are categorized according to their focused purposes and clinical applications. Reprints of the original papers may be obtained by contacting Pulse Metric, Inc. or their original authors.
Topics
Methods and Clinical Validation
24 hour Ambulatory Monitoring and Circadian Variation
Hypertension and Genetic Risk (Preventative Cares)
Effects of Hypertensive Drugs and Treatments
Hypertension and End-Organ Damage
Hypertension and Cardiovascular Epidemiology
Hypertension in Pregnancy
Monitoring of Valvular and Cardiac Problems
Others
Methods and Clinical Validation
A New Non-invasive Method for Obtaining Arterial Pressure Waveforms: Assessment of Vascular Compliance and Validation with Catheter Data
Brinton TJ, Cotter B, Brown DL, Baddour P, Voung A, Chio SS, Calisi C, DeMaria AN., (Circulation 1994; 90: I445A)
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Development and Validation of a Non-invasive Method to Determine Arterial Pressure and Vascular Compliance
Brinton TJ, Cotter B, Kailasam MT, Brown DL, Chio SS, O'Connor DT, DeMaria AN., (Am. J. of Cardiology, 1997; 80: 323-330
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The Development and Validation of a New Non-Invasive Method to Evaluate Ventricle Function during Routine Blood Pressure Monitoring
Brinton TJ, Hu WC, Chio SS, Liu CP, (Am. J. Hypertension 1997; 10: 60A)
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Validation of Pulse Dynamic Blood Pressure Measurement by Auscultation
Brinton TJ, Walls, ED, Chio SS, (Blood Press. Monitor. 1998; Vol.3, No.2: 121-124)
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Age-based Differences between Mercury Sphygmomanometer and Pulse Dynamic Blood Pressure Measurements
Brinton TJ, Walls ED, Yajnik AK, Chio SS, (Blood Pressure Monitoring 1998, Vol.3, No.2: 125-129)
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24 hour Ambulatory Monitoring and Circadian Variation
Corresponding Arterial Compliance and Pulse Pressure Measurement During 24-Hour Ambulatory Monitoring
Brinton TJ, Neutel JM, Walls ED, Chio SS, Tai LC, Franklin SS, Smith DHG, Weber MA, (Am. J. of Hypertension, 1996; 9: 56A)
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Corresponding Pulse Pressure and Arterial Compliance Variations During Ambulatory Monitoring., in "Time-Dependent Structure and Control of Arterial Blood Pressure"
Brinton TJ, Neutel JM, Chio SS, Walls ED, Tai LC, Franklin SS, Smith DHG, Weber MA., (the Annals of the New York Academy of Sciences, 1996; 783:310-312)
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A New Technology to Determine Circadian Blood Pressure and Arterial Compliance Variations During Ambulatory Monitoring
Brinton TJ, Neutel JM, Walls ED, Chio S-S, Smith DHG, Franklin SS, Weber MA, (Presented at the Italian Society of Chronobiology Scientific Meetings, 1996.)
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Hypertension and Genetic Risk (Preventative Cares)
Non-invasive Arterial Pulse Waveform Analysis in Hypertension: Development of a Method, and Early Compliance Changes in Subjects at Genetic Risk of Hypertension
Kailasam MT, Brinton TJ, Wu RA, Hu G, Chio SS, Cervenka JH, Parmer RJ, O'Connor DT. (American Journal of Hypertension 1994; 7: 86A)
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Arterial Compliance by Cuff Sphygmomanometer: Application to Hypertension and Early Changes in Subjects at Genetic Risk
Brinton TJ, Kailasam MT, Wu RA, Cervenka RT, Chio SS, Parmer RJ, DeMaria AN, O'Connor DT, (Hypertension, 1996; 28: 599-603)
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Effects of Hypertensive Drugs and Treatments
Arterial Compliance by Cuff Sphygmomanometer: Application to Hypertension and Early Changes in Subjects at Genetic Risk (Effects of ACE Inhibition and Calcium Channel Blockade treatments were also studied and reported in this paper.)
Brinton TJ, Kailasam MT, Wu RA, Cervenka RT, Chio SS, Parmer RJ, DeMaria AN, O'Connor DT. (Hypertension, 1996; 28: 599-603)
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Adrenergic Beta-Blockade with Intrinsic Sympathomimetric Activity may Attenuate Improvement in Vascular Compliance during Exercise
Liu CP, Brinton TJ, Walls ED, Lin SL, Chio SS, Chiang HT, (Presented at 12th Annual Scientific Meeting of The Am. Soc. of Hypertension, San Francisco, April, 1997)
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Angiotensin Converting Enzyme Inhibitor Increases Vascular Compliance More than Adrenergic Beta-Blockade Despite Similar Blood Pressure Reduction
Liu CP, Brinton TJ, Tseng CJ, Chiou CW, Lin SL, Chio SS, Chiang HT, (Presented at the 8th European Meeting on Hypertension, European Society of Hypertension, Milan, Italy, June 1997)
Abstract Not Available
Angiotensin Converting Enzyme Inhibitors Improve Vascular Compliance and Pump Performance in Hypertensive Patients
Brinton TJ, Walls ED, Hu W-C, Hsu T-L, Chio S-S, Chang M-S, Liu C-P, (Presented at the International Society of Hypertension 16th Scientific Meetings, 1996.)
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Hypertension and End-Organ Damage
The Compliance versus Pulse Pressure Relation: A Potential Indicator of Decreased Load Adaptations in Hypertension
Brinton TJ, Neutel JM, Walls ED, Chio SS, Tai LC, Franklin SS, Smith DHG, Weber MA, (Presented at Am. Society of Hypertension 11th Annual Scientific Meetings, 1996)
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The Correlation of Arterial Blood Pressures and Compliance vs. LV Hypertrophy in Essential Hypertension
Li TD, Liu YC and Han B, (Translation of the Paper in Chinese, presented at "The 11th Symposium on Cardiovasology of PLA", April 24-28, 1998, Shanghai, China)
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Hypertension and Cardiovascular Epidemiology
Race (Black-White) and Gender Differences in Brachial Artery Compliance and Cardiac Contractility in Healthy Young Adults: The BOGALUSA Heart Study
Urbina EM, Elkasbany A, Brinton T, Walls D, Pickoff AS, Berenson GS, (Am. J. Hypertension 1997; 10: 207A)
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Hypertension in Pregnancy
Brachial Artery Compliance Decreases During Pregnancy
Grossman EB, Brinton TJ, Cunningham D, Walls, ED, Chio, SS, (Am. J. Hypertension April, 1998; 11: 184A.)
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A New Technique to Evaluate Arterial Compliance Changes During Pregnancy
Brinton TJ, Chio SS, Walls ED, Cunningham D, Grossman EB, (11th World Congress of International Society for Study of Hypertension in Pregnancy, ISSHP, Meeting presentation, Oct. 1998, Kobe, Japan)
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Monitoring of Valvular and Cardiac Problems
A New Non-Invasive Method for Detection and Assessment of Aortic Regurgitation During Routine Blood Pressure Recordings
Brinton TJ, Hsu TL, Kwan OL, Liu CP, Chang MS, Chio SS, DeMaria AN, (J. Am. College of Cardiology, 1996; 27: 87A)
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The Assessment of Systemic Vascular Compliance During Cardiac Output Measurement to Evaluate Cardiovascular Loading Status
Hu WC, Hsu TL, Brinton TJ, Tai LC, Chio SS, Wang SP, Chang MS, Liu CP, (J. Am. College of Cardiology, 1996; 27: 119A)
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Suprasystolic dP/dt max Obtained by Cuff Sphygmomanometer Traces Discriminates Subjects with Impaired Contractile Cardiac Function
Muscolo M, Germano G, Angotti S, et. al., (Am. J. Hypertension 1997: 10: 71A)
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The (dP/dt)max Derived from Arterial Pulse Waveform during 24 hr Blood Pressure Oscillometric Recording
Germano G, Angotti S, Muscolo M, et.al., (Blood Pressure Monitoring 1998; 3:213-216)
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Others
Age Based Differences Between Oscillometric and Auscultatory Measurement Techniques
Brinton TJ, Walls ED, Chio SS, (Am. J. of Hyper., 1996; 9: 105A)
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Pharmaceutical Care in Rural Community Pharmacy Clerkships: Emphasis on Developing Computer Skills to Enhance Patient Education
Miller LG, Jungnickel PW and Scott DM, (Am. J. Pharmaceutical Education 1996; 60: 249-255)
No Abstract Available
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